Inflammatory Breast Cancer International Consortium | IBC-IC HomepageInflammatory Breast Cancer International Consortium | IBC-IC

Kenneth L. Van Golen, PhD

Researcher

Title(s)

  • Associate Professor of Biological Science, University of Delaware
  • Senior Research Scientist, Helen F. Graham Cancer Center

Location(s)

  • University of Delaware
  • Dept. of Biological Sciences
  • 320 Wolf Hall
  • Newark, DE, 19716
  • United States of America
  • Phone: 302.831.2669

Research and Clinical Interests

IBC-Focused Research

Since 1996, my research has been focused on understanding the biology of Inflammatory Breast Cancer (IBC). In 1999 my laboratory found that RhoC GTPase, a member of the Rho subfamily of the Ras-superfamily of monomeric G-proteins, is overexpressed and active in IBC. RhoC drives the invasive and metastatic capabilities of IBC and is also a prognostic marker for particularly aggressive breast cancers. Much of my research over the years has focused on RhoC biology and its role in IBC progression.

Currently, my laboratory is concerned with studying various aspects of IBC biology with a main focus on what makes this disease so aggressive and invasive. Studies in my laboratory have expanded from focusing on RhoC GTPase to scientific model development, microenvironment interactions, the biology of skin metastases, unique signal transduction pathways and development of new therapeutic agents.

Affiliated IBC-IC Center(s)

  • University of Delaware
  • Newark, DE, 19716
  • Research Center

Join IBC-IC

Become part of our international consortium of researchers, clinicians, advocates and centers worldwide dedicated to ending IBC.

IBCIC.org makes every effort to keep researcher information as up-to-date as possible.
Contact this researcher to confirm any information regarding his or her profile.